학회: Aesthetic surgery - 2012 and beyonnd - Methods for frozen fat tissue injection to have less complications |
Methods for frozen fat tissue injection to
have less complications.
Heeyoung Lee. M.D., Ph.D., Hyunjin Yang. M.D.
Baroyl &
Kangnam Plastic Surgery., Seoul, Korea
Frozen fat
tissues are composed with adipocytes(90-95%), stromal structures with stem
cells, but all cells are not viable. Fortunately, stromal scaffolds like structures
can induce stem cells to move dead graft from recipients area, then new stem
cells would be differentiate to new adipocytes. They contains numerous natural
human growth factors bind to collagen, laminin, elastin etc. But volume can be
maintained much lesser than fresh fat grafts.
We have been
used modified frozen fat to have less complications like oil cysts, unwanted
adhesions, too much absorption.
In direct uses,
We always centrifuge after thawing with high rpm and metal weight to remove
free oil then several adjuvant materials could be used.
1. newly
isolated stem cells(autologous or homologous) from new fat harvests or already
being proliferated.
2. dried
collagen powders
3. PRP
4. H/A filler
5. Barbed
threads
As conclusions,
Frozen dead fat tissues
also can be grafted, even though it just have limited effects because of cheap
costs, simplicity, safety, long lasting volume effects.
Several additives and process modification methods could improve clinical results, so authors have been injected frozen fat stored within 1 year period.